Hypersensitivity reaction to dapsone: report from Malaysia

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Hypersensitivity reaction to dapsone: report from Malaysia.

Three patients who developed hypersensitivity reaction at varying intervals after the initiation of dapsone therapy are described. Two of them had leprosy whereas the other had dermatitis herpetiformis. Their clinical manifes­ tations were not uniform. Although fatal complications have been reported, the unique role played by dapsone in the treatment of leprosy and the importance of recognizing...

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Hypersensitivity Reaction to Local Anesthetic in Dentistry: A Case Report

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Severe dapsone hypersensitivity syndrome.

Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report the case of a 21-year-old female patient with dapsone hypersensitivity syndrome. The clinical presentation mimicked a vir...

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Hypersensitivity reactions to dapsone: a systematic review.

Dapsone is widely used in the treatment of leprosy and several chronic inflammatory dermatological conditions. Hypersensitivity reactions to dapsone are potentially fatal adverse drug reactions with unknown prevalence and risk factors. We performed a systematic review covering all reported cases of hypersensitivity reactions, in order to systematically summarize the published evidence on preval...

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ژورنال

عنوان ژورنال: Leprosy Review

سال: 1984

ISSN: 0305-7518

DOI: 10.5935/0305-7518.19840044